6. 16. The local cortical amyloid deposits in general paresis correspond to beta-amyloid.


The immunocharacterization of the cortical amyloid depsits were analyzed in 8 patients with clinically, serologically and pathologically confirmed general paresis with slowly progressive dementia (atrophic form of dementia paralytica). A panel of antibodies recognizing various epitopes of the Aβ peptide, showed that the amyloid deposits correspond to Aβ.